Wikiveda

Whether ’tis nobler in the mind to suffer
The slings and arrows of outrageous fortune,
Or to take arms against a sea of troubles,
And by opposing end them?

— Balwinder Shaikh’s Pir in Amrit

Mama Beeb reports that India is putting together an ayurpedia to fight inappropriate patents in developed countries (via Slashdot): Claim: 80% of U.S. patents on medicinal plants by 2000 were of Indian origin

In a quiet government office in the Indian capital, Delhi, some 100 doctors are hunched over computers poring over ancient medical texts… One of them is Jaya Saklani Kala, a young ayurveda doctor, who is wading through a dog-eared 500-year-old text book for information on a medicine derived from the mango fruit…. putting together a 30-million-page electronic encyclopædia of India’s traditional medical knowledge…

Dr Vinod Kumar Gupta, who is leading the traditional wealth encyclopaedia project… reckons that of the nearly 5,000 patents given out by the US Patent Office on various medical plants by the year 2000, some 80% were plants of Indian origin… … in most of the developed nations like United States, “prior existing knowledge” is only recognised if it is published in a journal or is available on a database…

Mogambo is displeased

The ambitious $2m project, christened Traditional Knowledge Digital Library, will roll out an encyclopaedia of the country’s traditional medicine in five languages – English, French, German, Japanese and Spanish – in an effort to stop people from claiming them as their own and patenting them. The electronic encyclopædia, which will be made available next year, will contain information on the traditional medicines, including exhaustive references, photographs of the plants and scans from the original texts…

… ayurvedic texts are in Sanskrit and Hindi, unani texts are in Arabic and Persian and siddha material is in Tamil language… there are some 54 authoritative ‘text books’ on ayurveda alone, some thousands of years old… [Link]

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The Wonders of Dinosaur Dung

For today’s Science Friday I wanted to talk about crap. Dinosaur crap that is. About two years ago I came across the word “coprolite” in a paper I was reading. I have a bookmark set to Dictionary.com so I tend to look up many words throughout the day (mostly because unlike most desis I am a shockingly poor speller). To my surprise “corpolite” was yet another name that humanity has provided for feces:

The Indus Valley Civilization could have used a few of these

cop·ro·lite n.
Fossilized excrement. [Link]

Well okay then. I am quite sure several of you will be sharing this new knowledge with someone tonight. You see, corpolite is a paleontologist’s dream. Not only can you figure out if the animal that “dropped” it was a carnivore/herbivore/omnivore, but you can also tell which plants existed at the time. An article in the Journal Science today is titled, “Dinosaur Coprolites and the Early Evolution of Grasses and Grazers,” and has Dr. Vandana Prasad of Lucknow as the first author (paid subscription required):

Silicified plant tissues (phytoliths) preserved in Late Cretaceous coprolites from India show that at least five taxa from extant grass (Poaceae) subclades were present on the Indian subcontinent during the latest Cretaceous. This taxonomic diversity suggests that crown-group Poaceae had diversified and spread in Gondwana before India became geographically isolated. Other phytoliths extracted from the coprolites (from dicotyledons, conifers, and palms) suggest that the suspected dung producers (titanosaur sauropods) fed indiscriminately on a wide range of plants. These data also make plausible the hypothesis that gondwanatherian mammals with hypsodont cheek teeth were grazers.

Translate to English please: this means that ~70 million years ago a lot of really large dinosaurs were grazing on grass all over the chunk of land that eventually broke away from the supercontinent Gondwana to become the Indian sub-continent (before it once again recombined like the present day). We can always rely on good old National Geographic to break it down for the laymen:

Coprolites are very common in the area and are often found in rocks that have been worn down by weather. Based on their common association with titanosaur bones, many of the dung fossils probably come from the massive plant-eating reptiles.

The finding is the first indication that grasses evolved before the dinosaurs went extinct.

Fossil evidence had suggested that grasses evolved along with early plant-eating mammals. Hoofed animals with high-crowned teeth suitable for chewing grass first began to appear about 25 million years ago.

But the grass minerals in the Indian coprolites were much older than the hoofed mammals and were already diverse. Five different species were evident, which means that grasses likely diversified substantially before the end of the late Cretaceous.

Imagine that. Dinosaurs were doing almost the same job millions of years before the sacred cow began eating grass all over India (and tilling the fields), thus sustaining the Indus Valley Civilization. This immediately caused me to imagine a Flintstones type universe in which the dinosaurs may have gone on to become sacred, if only they had survived extinction and been domesticated.

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Magic Inc.

Bubble boy Ram Sabnis helped an inventor complete his decade-long quest to create a new kids’ toy: the first bubbles with disappearing color, so they won’t stain your kids or your floor (see photos). Like sticky notes, their impermanence is their selling point (via Boing Boing). I knew that textile industry would come in handy someday!

Ram Sabnis is a leader among a very small group of people who can point to a dye-chemistry Ph.D. on their wall. Only a handful of universities in the world offer one, and none are in the U.S. (Sabnis got his in Bombay). He holds dozens of patents from his work in semiconductors (dying silicon) and biotechnology (dying nucleic acids)…

Sabnis told them he’d have it ready to market in a year… “This is the most difficult project I have ever worked on,” Sabnis says now… For months, he ran 60 to 100 experiments a week, filling notebooks with sketches of molecules, spending weekends in the library studying surfactant chemistry, trying one class of dyes after another…

He synthesized a dye that would bond to the surfactants in a bubble to give it bright, vivid color but would also lose its color with friction, water or exposure to air… go away completely, as though it had never been there. When one of these bubbles breaks on your hand, rub your hands together a few times and look: Poof. Magic. No more color… [Link]

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Evolution and Religion: A Science Friday smackdown

For today’s Science Friday, I want to jump right into the center of the culture wars. From Tuesday’s elections, two results in particular will affect the way that science is taught in parts of our country. First, the Kansas Board of education voted 6-4 to weaken evolution teaching in its classrooms. Second, voters in Dover, PA swept eight pro-Creationist school board members out of office and replaced them with eight anti-creationists.

The Kansas Board of Education has approved science standards that support the theory of intelligent design and cast doubt on Darwin’s theory of evolution. The final vote was 6-4 in favor of intelligent design. [Link]

Voters in rural Dover, Pennsylvania, on Tuesday ousted eight school board members who favor mentioning the concept as an alternative to evolution. The newly elected board members are opponents of the concept, which critics say promotes the Bible’s view of creation and violates the constitutional separation of church and state. [Link]

The latter action prompted this from good ‘ole Pat Robertson:

Conservative Christian broadcaster Pat Robertson told citizens of a Pennsylvania town that they had rejected God by voting their school board out of office for supporting “intelligent design” and warned them Thursday not to be surprised if disaster struck…

“I’d like to say to the good citizens of Dover: if there is a disaster in your area, don’t turn to God, you just rejected Him from your city,” Robertson said on his daily television show broadcast from Virginia, “The 700 Club” [Link]

This week’s Time magazine features a very clear and concise appeal from commentator Eric Cornell, calling all scientists to action:

…as exciting as intelligent design is in theology, it is a boring idea in science. Science isn’t about knowing the mind of God; it’s about understanding nature and the reasons for things. The thrill is that our ignorance exceeds our knowledge; the exciting part is what we don’t understand yet. If you want to recruit the future generation of scientists, you don’t draw a box around all our scientific understanding to date and say, “Everything outside this box we can explain only by invoking God’s will.” Back in 1855, no one told the future Lord Rayleigh that the scientific reason for the sky’s blueness is that God wants it that way. Or if someone did tell him that, we can all be happy that the youth was plucky enough to ignore them. For science, intelligent design is a dead-end idea.

My call to action for scientists is, Work to ensure that the intelligent-design hypothesis is taught where it can contribute to the vitality of a field (as it could perhaps in theology class) and not taught in science class, where it would suck the excitement out of one of humankind’s great ongoing adventures.

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America’s Top Young Scientist

Earlier this week The Discovery Channel handed out awards for its 2005 Discovery Young Scientist Challenge. Who took ‘America’s Top Young Scientist of the Year’ award? Meet Neela Thangada of San Antonio, TX. From Rediff.com:

Neela, of San Antonio, Texas, was adjudged ‘America’s Top Young Scientist of the Year’which carries a $20,000 scholarship – for her science project on plant cloning.

…student of Keystone Junior High School, won the top prize for her science fair project titled ‘Effects of Various Nutrient Concentrations on the Cloning of the Eye of Solanum Tuberosum at Multiple Stages.’ Her skills of leadership, teamwork, scientific problem solving, critical thinking, and oral and written communication skills earned her the title of ‘America’s Top Young Scientist of the Year’, organisers say.

“I am very excited and happy to win this prize,” Neela told rediff India Abroad. “I did not expect to win, so it was a shock to me.” She said the contest is a great programme, which helps students get interested in science and take that interest to the next level. She plans to continue research at her high school, with the ultimate goal of becoming a professor of medicine.

Neela’s research was inspired by a biology textbook’s idea of a potato cloning experiment. She wanted to determine how different nutrient concentrations affected the multiple stages of growth in a potato. In her experiment, she removed 60 shoot tips from growing potatoes.

After sterilizing the tips, she excised the bottom two segments, and placed each in a test tube of half-strength or full-strength nutrient solution before incubating them.

Cloning? I don’t think they look favorably upon cloning in conservative Texas. It’s great to see that Indian parents are now allowing their kids aspire to be a professor of medicine and not just common doctors . Nine of the forty finalists were in fact of South Asian origin. Second place went to Nilesh Tripuraneni of Fresno, CA:

Nilesh had heard about hydrogen-powered cars but understood that producing hydrogen requires fossil fuels. He sought to find a more environmentally friendly approach through solar hydrogen production.

Nilesh built a solar-powered device that ran an electric current through a beaker full of saltwater. The result: electrolysis, by which water is split into hydrogen and oxygen. By clever manipulation of various gas laws, Nilesh measured the temperature, pressure, and volume of the hydrogen gas produced. He found that seawater produced almost as much hydrogen as solutions containing sulfuric acid or sodium hydroxide. [Link]

That there is an engineer in the making folks.

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Bird Flu, Indian Reverse Engineers and Mangosteens, Oh My!

I sometimes hang out at Brad DeLong’s blog, where apparently Razib thought I was a dude. Yesterday DeLong wrote a Cipla's Chief, Yusu Hamiedpost about Tamiflu, the Roche patented drug which is the one of the only plausible defenses against the dreaded Avian influenza or Asian Bird Flu. DeLong was mostly concerned with the domestic policy and economic ramifications of nationalizing a patent in times of emergency and stockpiling a drug ahead of time, but as with Sepia Mutiny, the comments can be most educational–and that’s how I found out that clever Cipla is at its Robin Hood reverse engineering tricks again. Bird flu is, of course, a global issue:

Cipla, an Indian producer of generic drugs, is preparing to become an alternative producer of oseltamivir phosphate, an antiviral drug better known by the brand name Tamiflu.Cipla plans to offer Tamiflu in the Indian market and in 49 less-developed countries where the company already sells AIDS treatments, Hamied says. The legality of the introduction in India, where pharmaceutical patents started to be recognized this year, is uncertain.

Hamied says he will withdraw Tamiflu from the Indian market if Roche’s patent is recognized.  (Link.)

A Roche spokesman, Terry Hurley, said that the company ”fully intends to remain the sole manufacturer of Tamiflu.” . .Making the drug involves 10 complex steps, he said, and the company believes that it’ll take another company ”two to three years, starting from scratch,” to produce it. Hamied dismissed that claim, saying that he initially thought it would be too hard but that his scientists had finished reverse-engineering the drug in his laboratories two weeks ago. He said he could have small commercial quantities available as early as January 2006. Asked if he thought Hamied was making an idle boast, Hurley declined to comment. Hamied said he would sell generic Tamiflu ”at a humanitarian price” in developing nations and not aim at the US or European market. ”God forbid the avian flu should strike India,” he said. ”There is no line of defense.” (Link.)

What does this have to do with mangosteens? I’m glad you asked!

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Science Fridays?

I was thinking of starting up “Science Fridays” here on SM.  Let’s face it, there are a lot of science geeks and engineers that read SM on a daily basis who aren’t being catered to.  I think our long term growth strategy should include reaching out to this key demographic.  Why Friday?  Two reasons.  First, the two most prestigious peer-reviewed journals Science and Nature are reported on in the media on Fridays (though they usually come out on Thursday).  More importantly however I usually have more time to blog on Fridays (the rest of the week I am busy doing science-geek things).   This being SM I will of course look for the desi connection in science stories.  So without further pomp here we go.  This week’s theme will be Cryptozoology.  The first story I bring you is a tip from SM reader Marvin Thomas who writes to us about something that washed up on a beach in Tamil Nadu recently because it was supposedly dislodged by the Tsunami from months ago.  First watch the following clip [via Giantology]:

If you remember, Vinod blogged about ancient ruins that were uncovered as a result of the Tsunami.  This creature was supposedly buried close by.  But according to the “reporter” Rupa Sridharam in this “news clip” the bones of this creature just washed up/was unburied now.  Luckily SM has a paleontologist on staff to definitively tell you that this is a hoax.  Even if you can’t see the fake special effects it’s obvious that whoever filmed this doesn’t know the first thing about science.  First off they sent in archeologists to do a paleontologist’s job.  I HATE it when people mess stuff like this up.  Remember Top Gun?  Kelly McGillis’s character was described as a “civilian astrophysics instructor.”  Why the hell would someone that specialized in stars and globular structures be sent in to teach test pilots?  That’s just stupid.

Currently Snopes.com has this case (hoax or not) categorized as “undetermined.”

It’s probably safe to say that the clip itself is not a genuine news report, as no other news outlets have reported on this amazing find. We don’t yet know the source of the video — it could be something taken from a television or film drama, a viral promo for some type of upcoming entertainment offering (such as a video game), or just something created for the sake of perpetrating an amusing hoax.

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Fault Lines can’t be controlled

Every Geologist has the same macabre dream.  They want to be as close to the fault as possible when the big one hits.  Any geologist that tells you different is lying so as not to upset your sensibilities.  The first three months of this year I spent nearly every weekend camping in the rugged mountains near the San Andreas Fault while constructing a geological map of the area.  On every drive out the professor would smile devilishly and then say “maybe the Big One will hit this weekend.”

Previously I blogged about the extreme dangers of the world’s most unforgiving battlefield, high in the Siachen Glacier near the Line of Control in Kashmir (Manish followed up with some stats).  As if the hail of artillery rounds, machine-gun fire, and extreme cold weren’t enough, over the weekend the soldiers manning their outposts had to deal with a massive Earthquake almost directly beneath them.  How did those soldiers fair during the Earthquake?  That is a secret held close by both sides for good reason.  What men with guns can’t dislodge, an Earthquake can manage with ease.

ISLAMABAD: The Army General Headquarters has asked the Ministry of Water and Power to restore power to several sensitive military installations, which collapsed in the earthquake, along the Line of Control (LoC) in Azad Jammu and Kashmir (AJK), a government official told Daily Times.

The Water and Power Development Authority (WAPDA) was providing electricity to AJK from the Muzaffarabad Grid Station through a single point electricity provision system, while AJK Electricity Board was responsible for power distribution in the area.

The official said that the Muzaffarabad Grid Station supplied electricity to all sensitive military installations and pickets, but the earthquake has completely destroyed the system. [Link]

and on the Indian side:

Twenty-six security personnel, including 21 Army jawans, were killed and scores of others injured as the massive earthquake damaged bunkers and barracks along the Line of Control (LoC) in Baramulla, Kupwara and Poonch districts of Jammu and Kashmir today.

The Army has lost 21 soldiers due to bunkers caving in and damage to barracks along LoC in Rampur, Uri, Baramulla and Tangdhar sectors, a defence spokesman told PTI. [Link]

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Nanda wins ignominious Ig Nobel

Mahatma Gandhi may never have won a Nobel, but Gauri Nanda makes it all ok.

The Ig Nobels are the Hasty Puddings of the science world. They’re given out for the most pointless or humorous scientific research, like one winning paper on how leeches react to beer and sour cream. (Like humans, I’m guessing they swell up and die.)

Nanda won last night for her annoying, you-must-get-out-of-bed alarm clock. She’ll make a perfect desi mom someday Congrats, Gauri!

ECONOMICS: Gauri Nanda of the Massachusetts Institute of Technology, for inventing an alarm clock that runs away and hides, repeatedly, thus ensuring that people DO get out of bed, and thus theoretically adding many productive hours to the workday.

The 2005 Ig Nobel Prizes were awarded on Thursday evening, October 6, at the 15th First Annual Ig Nobel Prize Ceremony, at Harvard’s Sanders Theatre… [Link]

Note that last night was their 15th ‘First Annual’ ceremony, like it’s my friends’ tenth 21st birthdays  Here’s more on Nanda. Past South Asia-related winners:

MATHEMATICS: K.P. Sreekumar and the late G. Nirmalan of Kerala Agricultural University, India, for their analytical report “Estimation of the Total Surface Area in Indian Elephants…”

PHYSICS: Deepak Chopra of The Chopra Center for Well Being, La Jolla, California, for his unique interpretation of quantum physics as it applies to life, liberty, and the pursuit of economic happiness. [REFERENCE: Deepak Chopra’s books “Quantum Healing,” “Ageless Body, Timeless Mind,” etc.]…

PEACE: Lal Bihari, of Uttar Pradesh, India, for a triple accomplishment: First, for leading an active life even though he has been declared legally dead; Second, for waging a lively posthumous campaign against bureaucratic inertia and greedy relatives; and Third, for creating the Association of Dead People…

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The Bugs Tell The Story

A fascinating article from a science blog I read from time to time – 

This year’s Nobel Prize in medicine or physiology was announced this morning. Barry Marshall and J. Robin Warren won for discovering that ulcers can be caused not by stress or genes but by a bacterium called Helicobacter pylori (shown here)

…Helicobacter infects half of all people on Earth…The scientists documented a surprising variety of genes in the bacteria. Each ethnic group they looked at carried a distinctive strain.

As scientists got to know the global variation of Helicobacter better, they began to discover a remarkable pattern. They mapped out an evolutionary tree of the strains of the bacteria and found that it lined up very well with the migrations of humans over the past 50,000 years. One study looked at the Ladakh province of northern India. Muslims and Buddhists have coexisted there for 1000 [years] but remain isolated from one another. It turns out that Muslim Ladakhs only carry a European strain of Helicobacter, while Buddhists carry a mix of European and East Asian bugs.

They might be neighbors, but that don’t mean they’re friends.

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