Who’s Fat? 50% of Indians Carry Obesity Gene

I recently wrote about the worldwide food price crisis, which has the potential to leave millions in the Indian subcontinent malnourished in the upcoming months and years. A number of commenters then wrote in to point out that middle-class Indians, who can afford to eat high-calorie, processed foods, have pretty unhealthy eating habits, and are rapidly growing obese.

It’s true, but it’s not only diet. The BBC has a recent article summarizing the findings of a recent study suggesting that 50% of people of Indian descent carry a gene that predisposes them to obesity.

The gene is located near the MC4R sequence, which has been linked by some scientists with binge eating:

The gene sequence sits close to – and possibly influences – a gene called MC4R, which regulates energy levels in the body by influencing how much we eat and how much energy we expend or conserve, and which has been directly implicated in rare forms of extreme childhood obesity.

The researchers discovered that the sequence is associated with a 2cm expansion in waist circumference, a 2kg gain in weight, and a tendency to become resistant to insulin, which can lead to type 2 diabetes. (link)

(Incidentally, a while ago we wrote about the growth of Type II diabetes amongst South Asians: here)

New Kerala actually gives a much more technical summary of the results of the study, for those who are interested: Continue reading

Thrown Your Baby off a Building Lately?

Yet another “bizarre ritual” from the desh…but to be honest, I’ve never heard of this at all before. Have you? Anyone know anything about this?

Muslims in western India have been observing a bizarre ritual – they’ve been throwing their young children off a tall building to improve their health. The faithful have been observing the ritual at a shrine in Solapur, in western India’s Maharastra, for more than five hundred years. They believe it will make their children strong and say no accidents have ever happened. link

Continue reading

Bye Bye Nalgene?

We may be seeing the end of the ubiquitous Nalgene bottle, like the one sitting on the corner of my office desk that I drink from continuously throughout the day. The Canadian government is about to declare bisphenol-a, or B.P.A, a toxic chemical:

The Nalgene is dead.

B.P.A. is widely used to make polycarbonate plastics, which are rigid and transparent like glass but very unlikely to shatter…Because animal tests have shown that even small amounts of the chemical may cause changes in the body, however, researchers have focused on food- and drink-related applications of B.P.A., like the popular Nalgene brand beverage bottles. [Link]

The US government may be moving in the same direction, albeit more slowly:

… a draft report from the United States Department of Health and Human Services’ National Toxicology Program endorsed a scientific panel’s finding that there was “some concern” about neural and behavioral changes in humans who consume B.P.A. [Link]

The debate about the health impact on humans will probably continue for a while, but one way or another, Nalgene’s days as the dominant water jug are over as people decide that they’d rather be safe than sorry. I’m probably going to be one of them, since I don’t have the expertise necessary to evaluate the health claims myself.

So how will I keep myself hydrated? Well, I’m thinking of rocking it old school. What would be better than a stainless steel jug and tumbler to keep in my office? You know, the kind with the rough edge that you can feel on the underside of your lip as you drink the water with the slightly metallic tang? Nalgene never induced nostalgia like this.

Now if only I could replace my office chair with a charpoy …

Continue reading

What’s wrong with medicine

Recently, I’ve read three articles by brown doctors (Darshak Sanghavi, Atul Gawande, and Sandeep Jauhar) all of which claim that there is something systematically wrong with the practice of medicine today. All three argue that we pay too much and get too little; Gawande goes the furthest by claiming that doctors and nurses routinely fail perform simple tasks they claim to be carrying out, thus endangering lives [Thanks Rahul].

Jauhar argues that poor incentives lead to gigantic amounts of waste in almost all medical practices:

In our health care system, where doctors are paid piecework for their services … overuse of services in health care probably cost hundreds of billions of dollars last year

Are we getting our money’s worth? Not according to the usual measures of public health. The United States ranks 45th in life expectancy, behind Bosnia and Jordan; near last, compared with other developed countries, in infant mortality; and in last place … among major industrialized countries in health-care quality, access and efficiency. [Link]

The other two go deeper than just the reimbursement system. They argue that doctors are not doing the routine tasks of their profession well, which reduces the quality of health care across the board and even kills patients:

… a team of researchers … reviewed children’s medical records from 12 major American cities and found that fewer than half of children got the correct medical care during doctor visits…A similar study of adult quality of care was published in 2003 with similar results. [Link]

Continue reading

The Biggest Malpractice Suit Ever?

This story broke last week, but I’m just starting to catch up on it now: in Las Vegas, more than 100 people have tested positive for Hepatitis C and HIV after being treated at the Endoscopy Center of Southern Nevada. Apparently, investigators have found that anesthesia needles were re-used on different patients without adequate cleaning, and in some cases, portions of the same dose of anesthesia was injected into multiple patients.

The person who founded the Center, who has also been its majority owner, is a doctor named Dipak Desai. Three class action lawsuits have been filed against the center, with more than 100 plaintiffs total. Doctor friends tell me it might be the biggest medical malpractice case in recent history (I have not been able to directly confirm this… any docs in the house?).

I haven’t come across anyone saying that Desai himself gave the order to use the syringes this way, though I gather that the anesthetists employed at the Endoscopy center were nurses rather than doctors (might be a little corner cutting there). Since the investigations started, the nurses employed at Desai’s clinics have given up their nursing licenses. As of now Desai has not given up his own medical license, though he has voluntarily agreed to not practice medicine until the investigations are complete. My own inclination is to “wait and see” before piling on against Desai: he ran several clinics, and employed many other doctors, nurses, and technicians. This particular policy, which has caused so much harm to so many people, may not have come from him.

Before this mess started, Desai was a very well-respected doctor in the state of Nevada; he had a $1 million contract with the University Medical Center, where he directed the gastroenterology department; and the governor had appointed him to the State Board of Medical Examiners. All of that is not to excuse him; rather, it helps give us some sense of the scope of this case. Incidentally, when two doctors working at his clinics had earlier complained about unsafe hygiene with syringes, the claims weren’t investigated.

I’m curious to know what people think about this case. Obviously, it doesn’t reflect the practices of Indian doctors more broadly (and I come from a medical family, so I’m quite proud of the contributions Indian-Americans have made in medicine in the U.S.). But it does seem like a terrible tragedy, and for the employees of this particular Endoscopy Center, a huge mess. Continue reading

Crown vs. Turban: Unravelling the truth

I am often amazed at the claims that so-called experts make, even in a court of law. For example, the government of Ontario recently defended its policy that Sikhs riding motorcycles should wear helmets (not a requirement in BC or Manitoba) by claming that turbans would unravel in the breeze, thus posing a risk to other motorists.

Born to be wild

… the Crown declared that an expert it had hired proved that turbans unravel rapidly in 100 km/h winds. The Crown’s test had been carried out by a professional engineer who purchased a mannequin head, mounted it on a stick and then placed the assemblage in a wind tunnel. [Link]

Say what? Turbans unravel at 60 mph? Have they ever seen a Sardar riding a motorcycle? Or riding a roller coaster? Or even sticking his head out of a moving vehicle? The paag stays on tight my friend.

To test this claim, the plaintiff, Baljinder Badesha of Brampton (can you say that 10 times fast?), tried to replicate the study. He drove down the Cayuga Speedway at … gasp, 110 kmh. Did his turban unravel and flutter into the wind like a wayward plastic bag? Ummm … no. It was fit to be tied.

Mr. Hutchison [Baljinder Singh’s lawyer] was unable to find a documented case anywhere in the world where a Sikh motorcyclist’s turban had unravelled. Skeptical, he persuaded the OHRC to authorize its own test. After he confronted the Crown with the dramatically different test result, prosecutors conceded that their engineer had grossly miscalculated the force of the wind he had generated to batter the imitation head, Mr. Hutchison said.

In fact, the device had been subjected to a 300 km/h wind. [Link]

That’s right – they used 180 mph winds in their test, more of a gale than the stiff breeze you get at 60mph. And even so, I’m not entirely convinced. I’ll bet if they used a real person with a real turban going 180 mph, it might still stay on. But in any case, given that driving at 300 kmh is illegal, the point is moot. Continue reading

Flying high with just one engine

The folks over at Cinematical.com have been taking an early peak at some of the films that will be playing at this year’s SXSW Film Festival in Austin. This one immediately caught my eye as a film that more people need to know about:

FLYING ON ONE ENGINE captures the story of the severely disabled Dr. Dicksheet, a man who has donated his surgical skills to the cause of alleviating suffering among India’s poor. The film both highlights the problems of cleft lip and other congenital deformities, and also tells the dramatic story of a person risking his life to help those in need. Emphasizing Dr. Dicksheet’s frailty, his surgical brilliance, and the spectacular effects of his actions, this film juxtaposes the Nobel Prize nominated surgeon’s godlike status alongside the incredible desperation of the Indian community in which he serves.

The website of The India Project which Dr. Sharadkumar Dicksheet (from Brooklyn) runs is filled with inspirational pictures and stories, so I am glad someone has made a documentary about his work to spread the word. He is an eight-time Nobel Prize nominee and although he is himself hobbled by sickness, his patients think of him as a “God” for the help he brings to their lives.

Continue reading

The mini Hercules

As a person who appreciates his time at the gym (and advocates fitness in general), I knew I had to post this story as soon as I read it earlier today. Meet India’s Aditya ‘Romeo’ Dev, the world’s smallest bodybuilder:

Unlike many dwarfs, Romeo is well proportioned, with a head circumference of 15in and a chest measurement of 20in.

Romeo said: “I’ve been training as a bodybuilder for the last two years and by now I think I must be the strongest dwarf in the world.

“I have always been fit but since I started working out, I have become famous for my strength. [Link]

I doubt very much that he is the strongest dwarf in the world, but I do admire his ambition. What I appreciate most about “Romeo” is that he just does his thing with confidence. One big fear some people have about going to the gym is that they will look weak in front of the rest of the “big muscle-bound” guys. As you can see from the pictures, Dev isn’t even afraid to wear Calvin & Hobbes shorts while working out:

Don’t stare without pinhole sunglasses

Finally, the media will have something from India besides the Little Superstar to talk about. At least this guy is a certified pimp.

Continue reading

Duh, only Royals can be inbred.

A British politician has caused quite a stir with his statements regarding the defective results of the arrangements Asians accede to…

A minister who warned about birth defects among children of first cousin marriages in Britain’s Asian community has sparked anger among critics.
Phil Woolas said health workers were aware such marriages were creating increased risk of genetic problems.
The claims infuriated the Muslim Public Affairs Committee (MPAC) which called on the prime minister to “sack him”. [BBC]

As far as Woolas is concerned, he’s bravely confronting a worrisome issue which is politically incorrect; he has been quoted as saying he has an obligation to bring this up. He isn’t attacking the marriages as illegal or even a religious problem, his point is that this is a cultural practice which should be examined. Children of such unions are 13x more likely to suffer from recessive disorders.

“The issue we need to debate is first cousin marriages, whereby a lot of arranged marriages are with first cousins, and that produces lots of genetic problems in terms of disability [in children]. If you talk to any primary care worker they will tell you that levels of disability among the… Pakistani population are higher than the general population. And everybody knows it’s caused by first cousin marriage….Awareness does need to be raised but we are very aware of the sensitivities,” [BBC]

Critics wonder about his motives, since his political position deals with the environment instead of health. The timing for this hullabaloo in the empire’s orchard is awesome:

His comments follow the storm sparked by the Archbishop of Canterbury, Dr Rowan Williams, who suggested some aspects of Islamic Sharia law could be allowed in Britain. [mirror]

Anti-green team, please note, both Woolas and the the cabinet minister who has his six, Geoff Hoon, are taking pains to point out that this conniption about cousin-coupling doesn’t involve the “wider Muslim community”; oh no, this backwardness is alll Asian.

The junior Minister has other vocal supporters besides Hoon: Continue reading

Urban legend becomes real?

There is an old and familiar urban legend about kidney thieves that prey upon unsuspecting travellers, stealing their bodily organs. The most common version involves a business traveller who goes out for a drink, gets knocked out, and wakes up in a bathtub full of ice with his kidneys missing.

According to Snopes, there have been no documented occurrences of travellers’ kidney being stolen. The roots of this story are probably an incident in 1989 where a Turkish man falsely claimed he had been lured to England with the promise of a job only to find his kidney removed. The story fell apart once it was revealed that he had advertised his kidney for sale, but not before the account had mutated and spread.

So you’ll have to understand that I was shocked, and a bit skeptical, to hear about roughly 600 kidneys stolen from poor people in India for transplant in rich foreigners:

Many of the donors were day laborers… picked up from the streets with the offer of work, driven to a well-equipped private clinic, and duped or forced at gunpoint to undergo surgery… The men said there were no postoperative medical checks and no discussion of money or other compensation.

Four doctors, 5 nurses, 20 paramedics, 3 private hospitals, 10 pathology clinics and 5 diagnostic centers were involved… The officials suspect that several private hospitals in Delhi and its suburbs were quietly complicit in Dr. Kumar’s work and treated patients recovering from kidney transplants.[Link]

Beyond my moral revulsion, I was also a bit confused as to why they were robbing people of body parts when there was already a voluntary (and still illegal) trade in kidneys. Generally speaking, one would prefer to buy rather than steal kidneys because the donors are less likely to go to the cops and because you’re less likely to have your gundas stage a coup and take all your money.

Continue reading