Paul Varghese made it to the semifinals on Last Comic Standing (via MD). Varghese is a Texan Malayalee who started doing stand-up comedy in 2001. More here:

Growing up was a struggle, Varghese had roving gangs of Malayalee doctors and aeronautical engineers brandishing slide rules in da hood. So, to stay off the streets, he kept it real at comedy clubs… My favorite desi stand-up is still the inimitable Russell Peters, a big, chubby Canadian upon whose dewy lashes perches the daemon of unapologetic cruelty.